Computer‐Aided Diagnosis in the Evaluation of Thyroid Nodules: A Study of Intra‐ And Inter‐Rater Reliability and Agreement

The computer-aided diagnosis system demonstrated predominantly moderate to almost perfect intra-rater reliability and moderate to strong inter-rater agreement across most evaluated features. The highest reproducibility was observed for "taller-than-wide," "texture," and "composition," whereas "shape" consistently showed lower agreement. These findings support the system's role as a reliable adjunct for standardizing thyroid nodule assessment, although its performance remains partially influenced by operational factors and warrants further multicenter validation.