Case reports demonstrate false-positive thyroglobulin results in benign lymph nodes, suggesting clinical caution.
Markedly elevated thyroglobulin (Tg) washout is often considered highly suggestive of metastatic differentiated thyroid cancer. We present two cases of false-positive Tg washout in cervical lymph nodes with benign pathology, notably in patients who were carriers of iron-handling disorders. These findings highlight the limitations of Tg washout as a standalone marker and the need for multimodal interpretation.
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Gohari et al. (2026) studied this question.
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