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Systematic review and meta-analysis reveal higher misdiagnosis risk of segmental aneuploidies in embryos, indicating caution is needed.
The results indicate that embryos with segmental aneuploidies have a significantly higher risk of misdiagnosis, especially in the PGT-A population. This highlights the need for caution when interpreting trophectoderm (TE) biopsy results involving segmental aneuploidies, to avoid misdiagnosis and the inadvertent discard of potentially viable embryos.
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Jiang et al. (2026) studied this question.
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