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April 1, 2026Asian Pacific Journal of Cancer PreventionOpen Access

Tumor Budding Significance as a Biomarker for Clinicopathology and Prognostic Evaluation in Gynecological Malignancy: A Bayesian Meta-Analysis

I Wayan Bagus Wisnu Jaya Wiguna Ni Wayan Armerinayanti Christo Timothy Mamangdean Ngakan Putu Mahayana Putu Mirah Wahyu Putri Kadek Meryndha Tungga Artha Maressa Simanjuntak Frengki Prabowo Wijayanto Suparada Khanaruksombat I Gde Sastra Winata

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Key Points

The aim is to assess the significance of tumor budding as a prognostic biomarker in gynecological malignancies.
Conducted a Bayesian meta-analysis of existing literature
Evaluated the association between tumor budding and clinicopathological features
Assessed the prognostic implications of tumor budding in patients with gynecological malignancy
Tumor budding shows a significant association with clinicopathological features
Strong correlation with worse prognosis in gynecological malignancies
Findings suggest that tumor budding could inform clinical assessments

Implication

Meta-analysis reveals tumor budding's significant association with prognosis in gynecological malignancy, indicating clinical importance.

Abstract

Tumor budding is significantly associated with clinicopathological features and prognosis in patients with gynecological malignancies.

Discussion

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Cite This Study

Wiguna et al. (2026) studied this question.

synapsesocial.com/papers/69d894ce6c1944d70ce05b43 https://doi.org/10.31557/apjcp.2026.27.4.1323

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Clinicopathologic and Prognostic Significance of Tumor Budding in Endometrial Cancer: A Systematic Review and Meta-AnalysisMeta-Analysis · 2026
2Exploring the Usefulness of Tumor Budding as a Histopathological Marker Compared to Tumor-Node-Metastasis (TNM) Staging in Breast Cancer2024 · 3 citations
3Tumor budding in invasive breast carcinoma: an emerging prognostic factor2024
4Tumor budding as a predictive factor of lymph node metastases and survival in endometrial cancer patients: A systematic review and meta‐analysisMeta-Analysis · 2026
5Tumor Budding in Gastric Carcinoma: Beyond Counting Cells at the Invasive Front—A Review of Current Evidence and Biological PerspectivesReview · 2026 · 3 citations

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Potential predictor of prognosis in breast carcinoma: Tumor budding2024
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