Does federated diagnostic meta-analysis produce HEART score performance estimates comparable to centralized patient-level data in emergency department chest pain patients?
Federated meta-analysis provides a scalable, privacy-preserving approach for multicenter evaluation of ED risk-stratification tools like the HEART score.
Federated diagnostic meta-analysis produced HEART score performance estimates closely aligned with those obtained from centralized patient-level data. This approach enabled scalable, privacy-preserving multicenter evaluation of ED risk-stratification tools while accommodating heterogeneity across practice settings.
Wang et al. (Wed,) studied this question.