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April 10, 2026International Journal of Critical Illness and Injury Science

Prognostic value of hematological ratios in sepsis: A prospective observational study of neutrophil-to-lymphocyte, platelet-to-lymphocyte, and monocyte-to-lymphocyte ratios

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Authors

NDNavanath DeokateJawaharlal Nehru Medical CollegeSASourya AcharyaJawaharlal Nehru Medical CollegeRPRajvardhan PatilJawaharlal Nehru Medical College

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Overview

Prospective observational study evaluates hematological ratios predicting outcomes in sepsis, suggesting implications for risk assessment.

Key Points

  • This study aims to evaluate the prognostic significance of NLR, PLR, and MLR in sepsis outcomes.
  • Prospective observational study design
  • Included 200 adult patients with sepsis
  • Calculated NLR, PLR, and MLR from complete blood counts
  • Used Sequential Organ Failure Assessment score for organ dysfunction
  • Performed statistical analyses including ROC curve analysis
  • Higher NLR and MLR were linked to longer hospital stays and need for mechanical ventilation
  • NLR showed good predictive accuracy for mortality with AUC of 0.797
  • PLR demonstrated moderate predictive accuracy for mortality with AUC of 0.707
  • No significant difference in inflammatory ratios between death and discharge groups

Cite This Study

Deokate et al. (2026) studied this question.

synapsesocial.com/papers/69d895796c1944d70ce067cehttps://doi.org/10.4103/ijciis.ijciis_94_25
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