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April 10, 2026Journal of Clinical Otolaryngology Head and Neck SurgeryOpen Access

Clinical Course of Surgical Treatment for Adult Obstructive Sleep Apnea and the Natural Course of Untreated Patients

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Authors

JLJaemin LeeHOHaejin OhHJHyo Beom Jang

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Overview

This retrospective study compares surgical outcomes with untreated cases in obstructive sleep apnea, highlighting implications for long-term management.

Key Points

  • The study evaluates long-term changes in the apnea-hypopnea index following surgical treatment for obstructive sleep apnea compared to untreated cases.
  • Retrospective analysis of 74 adults with obstructive sleep apnea (43 untreated, 31 surgical)
  • Conducted two separate polysomnographies for evaluations of surgical and untreated groups
  • Defined severity of sleep apnea using the apnea-hypopnea index (AHI)
  • Evaluated surgical outcomes versus untreated groups at <36 months and ≥36 months post-treatment
  • Applied multivariate regression analysis, adjusting for age and body mass index changes
  • The untreated group showed significant deterioration in AHI among moderate cases (p=0.025)
  • Surgical treatment group experienced significant AHI reduction within 36 months (p=0.001)
  • AHI began to rebound towards baseline after ≥36 months, alongside weight gain (p=0.005)
  • Post-surgery, AHI increased by 0.37/hr per month even after adjustments (p=0.001)
  • Surgical benefits are fully offset by 53.6 months due to weight gain and loss of anatomical support

Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/69d896046c1944d70ce07413https://doi.org/10.35420/jcohns.2026.37.1.9
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