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April 10, 2026Food and Feed ResearchOpen Access

Fermented Buffalo milk (dadih) powder with reduced water activity as parabiotics for protection against oxidative stress and liver injury

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Authors

ISIza Ayu SaufaniSMSri Anna MarliyatiEPEny Palupi

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Overview

Evaluates dadih powder's effectiveness in protecting against oxidative stress in a rat model, indicating its potential as a parabiotic food.

Key Points

  • The aim is to evaluate the protective effects of dadih powder on oxidative stress and liver injury in a rat model of metabolic syndrome.
  • Formulated dadih powder with modified cassava flour at varying concentrations (10%, 30%, 50%)
  • Evaluated physicochemical properties and LAB viability using the deGarmo method
  • Conducted an eight-week intervention on Sprague-Dawley rats with different diet groups (normal, high-fat, treated)
  • Collected blood and liver samples for biochemical and histological analyses after the intervention.
  • Identified the 10% MOCAF dadih powder formulation as most effective based on LAB viability
  • Significantly reduced malondialdehyde levels, indicating antioxidative effects
  • Histopathological analysis showed near-normal liver structure in the 0.670 mg/g treatment group, contrasting with severe liver damage in the high-fat diet group.

Cite This Study

Saufani et al. (2026) studied this question.

synapsesocial.com/papers/69d896166c1944d70ce07511https://doi.org/10.5937/ffr0-63007
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