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April 10, 2026Abdominal RadiologyOpen Access

Transperineal 3D vector magnetic resonance elastography of the prostate is feasible in men with benign prostatic hyperplasia and lower urinary tract symptoms

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Authors

CJCody JohnsonJGJuan Pablo Gonzalez-PereiraMGMatthew Grimes

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Overview

Demonstrates the feasibility of 3D magnetic resonance elastography to evaluate prostate stiffness in men with urinary symptoms, implying its potential clinical application.

Key Points

  • To assess the feasibility of 3D vector magnetic resonance elastography of the prostate using a novel transperineal passive driver in men with benign prostatic hyperplasia and urinary symptoms.
  • Conducted on 21 men with varying severity of urinary tract symptoms
  • Used multiparametric prostate MRI including pMRE on a 3.0T MRI
  • Measured prostate volume, prostatic urethra length, postvoid residual, and bladder wall thickness
  • Calculated shear stiffness and correlations with uroflowmetry data
  • Applied Kruskal-Wallis rank sum test and Spearman correlation for data analysis.
  • Men with moderate/severe symptoms had greater age and BMI
  • Higher TZ shear stiffness correlated with lower peak and average urine flow rates
  • Measured parameters showed significant interrelations, highlighting dysfunction risks in men with severe symptoms.

Cite This Study

Johnson et al. (2026) studied this question.

synapsesocial.com/papers/69d896406c1944d70ce079adhttps://doi.org/10.1007/s00261-026-05407-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analysis of Magnetic Resonance Elastography Prostate Biomarkers in Healthy and Lower Urinary Tract Symptoms Subjects2025
  2. 2The feasibility of MR elastography with transpelvic vibration for localization of focal prostate lesion2024 · 1 citations
  3. 3Feasibility of multifrequency MR elastography of the seminal vesicles in healthy men, benign prostatic hyperplasia, and prostate cancer2026
  4. 4Role of Pre-procedural MRI Parameters and Urodynamic Findings in Predicting Clinical Success After Prostate Artery Embolization2026
  5. 5Magnetic resonance fingerprinting of the bladder is feasible in men with lower urinary tract symptoms.2026