What question did this study set out to answer?

Evaluate the effects of testosterone on weight stability and compare hospital outcomes in major burn patients.

Exploring the Benefits and Side Effects of Testosterone Administration in Major Burn Patients

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Single-center cohort study evaluates testosterone effects on weight and outcomes in burn patients, suggesting therapeutic potential.

Evaluate the effects of testosterone on weight stability and compare hospital outcomes in major burn patients.
Retrospective cohort study at a single center including patients with >20% TBSA burns.
Patients divided into intervention (testosterone) and control (standard care) groups.
Collected data on demographics, weights, comorbidities, TBSA, BAUX score, length of stay, mortality, and adverse effects.
Total of 82 patients met inclusion criteria (26 intervention, 56 control).
Mean TBSA was higher in the testosterone group (45.2% vs 31.4%).
Mean hospital stay was significantly longer in the testosterone group (98.3 vs 44.2 days).
Weight loss was slower in the testosterone group (–0.29 kg/week vs –2.19 kg/week in control), suggesting weight stabilization.
Safety outcomes, including liver function abnormalities and thromboembolic events, showed no significant differences.

Wahaibi et al. (2026) studied this question.

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