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Clustering identifies physiological phenotypes of obstructive sleep apnea linked to type 2 diabetes, suggesting metabolic differences.
Data-driven clustering identified distinct physiological phenotypes of OSA. In addition to the Severe desaturation type, the REM-predominant type was also strongly associated with T2DM, underscoring the metabolic heterogeneity of OSA. Prospective studies are needed to determine causal relationships and evaluate phenotype-targeted interventions.
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Osawa et al. (2026) studied this question.
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