Findings show no significant link between MOTS-c polymorphism and polycystic ovary syndrome, suggesting minor involvement.
indicate that the MOTS-c gene (m.1382A>C) polymorphism shows no significant association with PCOS, and serum MOTS-c levels are comparable between individuals with PCOS and healthy controls, suggesting that MOTS-c may have a minor involvement in the pathophysiology of PCOS.
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Filibeli et al. (2026) studied this question.
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