Evolutionary trajectories, early diversification and species-specific amplification of the metazoan Inhibitor of Apoptosis (IAP) repertoire

Mélanie Ribeiro Lopes; Nicolas Parisot; Sergio Peignier; François Renoz; Patrice Bâa-Puyoulet; Emmanuelle Jousselin; Hubert Charles; Patrick Callaerts; Céline Brochier-Armanet; Federica Calevro

doi:10.1093/molbev/msag078/8539999

January 1, 2026

Evolutionary trajectories, early diversification and species-specific amplification of the metazoan Inhibitor of Apoptosis (IAP) repertoire

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Key Points

This research aims to investigate the evolutionary development and diversification of the inhibitor of apoptosis (IAP) repertoire across different metazoan species.
Analyzed genomic data across various metazoan species
Identified evolutionary trajectories of IAP proteins
Examined species-specific amplification patterns of IAP genes
Documented significant early diversification within the IAP repertoire
Observed variations in IAP gene amplification specific to certain species
Highlighted evolutionary trajectories consistent with metazoan phylogeny

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Implication

This research uncovers the evolutionary paths and species-specific features of inhibitor of apoptosis proteins in metazoans, indicating significant diversification.

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Lopes et al. (2026) studied this question.

synapsesocial.com/papers/69d8968f6c1944d70ce080ba https://doi.org/10.1093/molbev/msag078/8539999

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Evolutionary trajectories, early diversification and species-specific amplification of the metazoan Inhibitor of Apoptosis (IAP) repertoire

Key Points

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Implication

Abstract

Discussion

Cite This Study

Evolutionary trajectories, early diversification and species-specific amplification of the metazoan Inhibitor of Apoptosis (IAP) repertoire

Key Points

No abstract yet

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Implication

Abstract

Discussion

Cite This Study

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