Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism

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Population

Male C57BL/6J mice

Design

Preclinical

Follow-up

2 or 4 days

Authors

Discussion

Cold exposure activates glucose-handling genes in rodent BAT; leaves open translation to human thermogenesis or metabolic disease.

Population

Male C57BL/6J mice

Intervention

Cold exposure for 2 or 4 days

Outcome

Transcriptome of brown and white adipose tissues (BAT and WAT)surrogate

Cold exposure induces extensive gene expression changes related to glucose handling in activated brown adipose tissue.

Hao et al. (2014) studied this question.

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