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December 6, 2017New England Journal of MedicineOpen Access

Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis

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Why the study?

Does pharmacomechanical catheter-directed thrombolysis reduce the risk of post-thrombotic syndrome in patients with proximal deep-vein thrombosis?

Population

Patients with proximal deep-vein thrombosis

Authors

SVSuresh VedanthamVascular Medicine
Samuel Z. Goldhaber
Samuel Z. GoldhaberVascular / Pulmonary Vascular
JJJim A. JulianVascular Medicine

Discussion

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Implication

Should not change DVT practice; leaves open whether pharmacomechanical thrombolysis reduces post-thrombotic syndrome.

Structured PICO

Does pharmacomechanical catheter-directed thrombolysis reduce the risk of post-thrombotic syndrome in patients with proximal deep-vein thrombosis?

P
Population
Patients with proximal deep-vein thrombosis
I
Intervention
Pharmacomechanical catheter-directed thrombolysis
O
Outcome
Post-thrombotic syndrome

Pharmacomechanical catheter-directed thrombolysis is hypothesized to reduce the risk of post-thrombotic syndrome in patients with proximal deep-vein thrombosis.

Cite This Study

Vedantham et al. (2017) studied this question.

synapsesocial.com/papers/69d8afdcd2f7327e70ae3f98https://doi.org/10.1056/nejmoa1615066
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1The Long-Term Clinical Course of Acute Deep Venous Thrombosis1996 · 2,116 citations