The physical PEGylation significantly enhanced the entrapment and loading efficiencies of 5-FU into NPs formulated with PLGA and PCL. It also fostered the in vitro cytotoxicity of 5-FU-loaded NPs in both Daoy and HepG2 cells. Induction of early apoptosis was confirmed for some of the formulations.
No takes yet. Share an insight, caveat, or question.
Ashour et al. (2019) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: