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December 4, 2019Polymer Chemistry

Design and synthesis of a polyguanidium vector with enhanced DNA binding ability for effective gene delivery at a low N/P ratio

Zhiyong Chen Wei Huang Nan Zheng Yugang Bai

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Abstract

A polyguanidium polymer has extra affinity toward DNA and can mediate transfection efficiently at a low polymer to DNA ratio.

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Chen et al. (2019) studied this question.

synapsesocial.com/papers/69d8c4655c3030ff03d1a772 https://doi.org/10.1039/c9py01481k

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