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May 6, 2021MicrobiomeOpen Access

Androgen-induced gut dysbiosis disrupts glucolipid metabolism and endocrinal functions in polycystic ovary syndrome

Qixin Han Juan Wang Weiping Li Zi‐Jiang Chen Yanzhi Du

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Abstract

These findings indicate that androgen-induced gut microbiota dysbiosis may aggravate metabolic and endocrinal malfunction in PCOS. Video Abstract.

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Han et al. (2021) studied this question.

synapsesocial.com/papers/69d8ca3a270e68ba94bed84c https://doi.org/10.1186/s40168-021-01046-5

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Adolescent Girls with Polycystic Ovary Syndrome Have an Increased Risk of the Metabolic Syndrome Associated with Increasing Androgen Levels Independent of Obesity and Insulin ResistanceCross-Sectional Study · 2006 · 448 citations
2How and Why Men and Women Differ in Their Microbiomes: Medical Ecology and Network Analyses of the MicrogenderomeOriginal Research · 2019 · 122 citations
3Individual diet has sex-dependent effects on vertebrate gut microbiotaOriginal Research · 2014 · 653 citations
4Population-level analysis of gut microbiome variationCohort Study · 2016 · 2,396 citations
5Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of AutoimmunityOriginal Research · 2013 · 2,020 citations

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