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April 28, 2023Clinical & Translational OncologyOpen Access

Dipeptidyl peptidase 4 inhibitor reduces tumor-associated macrophages and enhances anti-PD-L1-mediated tumor suppression in non-small cell lung cancer

Bei Zuo Tao Li Xiaoyun Liu Shuling Wang Jianxiang Cheng Xiangqun Liu Wenjie Cui Hengliang Shi Chunhua Ling

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Abstract

Anagliptin can enhance PD-L1 blockade efficacy in NSCLC by inhibiting macrophage differentiation and M2 macrophage polarization, and combination therapy may be a promising strategy for treating PD-L1 blockade therapy-resistant patients with NSCLC.

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Cite This Study

Zuo et al. (2023) studied this question.

synapsesocial.com/papers/69d8cf5617a1cc0598d18973 https://doi.org/10.1007/s12094-023-03187-5

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