Investigation of post-therapeutic image-based thyroid dosimetry using quantitative SPECT/CT, iodine biokinetics, and the MIRD’s voxel S values in Graves’ disease

Post-therapeutic image-based doses absorbed in the thyroid resembled those of pre-therapeutic EANM method-based absorbed doses. Additionally, the post-therapeutic image-based method had the advantage of visualizing thyroid iodine distribution, thus determining local dose distributions at the time of treatment. From these points, we propose that post-therapeutic image-based dosimetry could provide an alternative to standard pre-therapeutic dosimetry to evaluate dose response.