Prostate-Specific Antigen–Based Screening for Prostate Cancer

This is the authors' abstract. We don't add key points for this paper.

PSA screening may reduce prostate cancer mortality risk but is associated with false-positive results, biopsy complications, and overdiagnosis. Compared with conservative approaches, active treatments for screen-detected prostate cancer have unclear effects on long-term survival but are associated with sexual and urinary difficulties.