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March 4, 2020Cancer312 citationsOpen Access

Global trends in intrahepatic and extrahepatic cholangiocarcinoma incidence from 1993 to 2012

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AFAndrea A. FlorioJFJacques FerlayAZAriana Znaor

Key Points

  • To examine global trends in the incidence of intrahepatic and extrahepatic cholangiocarcinoma from 1993 to 2012.
  • Analysis of incidence data from numerous countries worldwide over 20 years.
  • Review of underlying metabolic and infectious factors influencing incidence rates.
  • Increased incidence of intrahepatic cholangiocarcinoma and extrahepatic cholangiocarcinoma observed in most countries.
  • Metabolic and infectious factors are likely contributing to these rising incidences.

Abstract

In the 20 years examined, ICC and ECC incidence increased in the majority of countries worldwide. ICC and ECC incidence may continue to increase because of metabolic and infectious etiologic factors. Efforts to further elucidate risk factors contributing to these increases in incidence are warranted.

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Cite This Study

Florio et al. (2020) studied this question.

synapsesocial.com/papers/69d8f1371ab91f1400bed9e5https://doi.org/10.1002/cncr.32803
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