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November 30, 2017British Journal of CancerOpen Access

Tumour budding in oral squamous cell carcinoma: a meta-analysis

Alhadi Almangush Matti Pirinen Ilkka Heikkinen Antti Mäkitie Tuula Salo Ilmo Leivo

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Abstract

Tumour budding is a simple and reliable prognostic marker for OSCC. Evaluation of tumour budding could facilitate personalised management of OSCC.

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Almangush et al. (2017) studied this question.

synapsesocial.com/papers/69d8f1a3a5ecc596b5d18cce https://doi.org/10.1038/bjc.2017.425

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Depth of invasion, tumor budding, and worst pattern of invasion: Prognostic indicators in early‐stage oral tongue cancerCohort Study · 2013 · 337 citations
2Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysisPrognostic Study · 2017 · 221 citations
3Prognostic value of tumour budding in oesophageal cancer: a meta‐analysisPrognostic Study · 2015 · 58 citations
4Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaborationOriginal Research · 2012 · 374 citations
5Tumor Budding Is an Independent Prognostic Factor for Prediction of Lymph Node Metastasis in Oral Squamous Cell CarcinomaPrognostic Study · 2015 · 89 citations

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Development of a New Outcome Prediction Model in Early-stage Squamous Cell Carcinoma of the Oral Cavity Based on Histopathologic Parameters With Multivariate Analysis2017
Tumour budding activity and cell nest size determine patient outcome in oral squamous cell carcinoma: proposal for an adjusted grading system2017
Transcriptional upregulation of c-MET is associated with invasion and tumor budding in colorectal cancer2016

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