Elevation of IL‐17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders

Kailey Brodeur; Meng Liu; Daniel Ibanez; Mareike J. de Groot; Liang Chen; Yan Du; Eman Seyal; Raquel Laza‐Briviesca; Annette Baker; Joyce C. Chang; Margaret H. Chang; Megan Day‐Lewis; Fatma Dedeoğlu; Audrey Dionne; Sarah D. de Ferranti; Kevin G. Friedman; Olha Halyabar; Mindy S. Lo; Esra Meidan; Robert P. Sundel; Lauren A. Henderson; Peter A. Nigrović; Jane W. Newburger; Mary Beth F. Son; Pui Y. Lee

doi:10.1002/art.42680

Key Points

Determine whether elevation of IL-17 family cytokines distinguishes Kawasaki disease from other pediatric inflammatory disorders that mimic its clinical presentation.
Assessed cytokine profiles, specifically the IL-17 cytokine family, in pediatric patients with Kawasaki disease and clinical mimics.
Elevation of IL-17 family cytokines represents a characteristic hallmark of Kawasaki disease.
Elevated IL-17 family cytokine levels differentiate Kawasaki disease from clinically similar pediatric inflammatory conditions.

Implication

Observational analysis reveals elevated IL-17 family cytokines in Kawasaki disease, indicating their potential utility in distinguishing the illness from pediatric inflammatory mimics.

Abstract

Elevation of IL-17 family cytokines is a hallmark of KD and may help distinguish KD from its clinical mimics.

Discussion

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Cite This Study

Brodeur et al. (2023) studied this question.

synapsesocial.com/papers/69d8f8896715230d10bedd7e https://doi.org/10.1002/art.42680

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Elevation of IL‐17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders

Key Points

Implication

Abstract

Discussion

Cite This Study

Elevation of IL‐17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders

Key Points

Implication

Abstract

Discussion

Cite This Study

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