In patients undergoing TAVR, specific clinical and procedural factors (such as residual aortic regurgitation) increase the risk of infective endocarditis, a complication with high mortality.
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May flag higher-risk TAVR patients for endocarditis surveillance; leaves open whether modifying factors reduces incidence.
Among patients undergoing TAVR, younger age, male sex, history of diabetes mellitus, and moderate to severe residual aortic regurgitation were significantly associated with an increased risk of infective endocarditis. Patients who developed endocarditis had high rates of in-hospital mortality and 2-year mortality.
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Regueiro et al. (2016) studied this question.
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