Why the study?
Balanced opioid-free anesthesia is feasible and desirable across surgical settings, but scientific evidence in thoracic surgery is lacking.
Does opioid-free anesthesia reduce complications and postoperative pain in patients undergoing thoracic surgery?
Population
904 patients undergoing thoracic surgery across 6 studies
Comparison
Opioid-free anesthesia vs opioid-based anesthesia
Design
Systematic review and meta-analysis of 1 RCT and 5 observational cohort studies
Authors
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May reduce complications in thoracic surgery; leaves open confirmation of pain benefits and practice change given limited studies.
Does opioid-free anesthesia reduce complications and postoperative pain in patients undergoing thoracic surgery?
Opioid-free anesthesia in thoracic surgery is associated with fewer postoperative complications and reduced opioid demand compared to opioid-based anesthesia.
D’Amico et al. (2022) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: