Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA

Chi Jin; Tuo Wang; Dongsheng Zhang; Peng Yang; Chuan Zhang; Wen Peng; Kangpeng Jin; Lu Wang; Jiahui Zhou; Chaofan Peng; Yuqian Tan; Jiangzhou Ji; Zhihao Chen; Qingyang Sun; Sheng Yang; Junwei Tang; Yifei Feng; Yueming Sun

doi:10.1186/s13046-022-02551-7

Abstract

NAT10 promotes the CRC progression through the NAT10/KIF23/GSK-3β/β-catenin axis and its expression is mediated by GSK-3β which forms a feedback loop. Our findings provide a potential prognosis or therapeutic target for CRC and remodelin deserves more attention.

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Jin et al. (2022) studied this question.

synapsesocial.com/papers/69d90eefcc20f7a91c3afff6 https://doi.org/10.1186/s13046-022-02551-7

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Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA

Abstract

Discussion

Cite This Study

Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA

Abstract

Discussion

Cite This Study

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