Does circumferential strain analysis provide better sensitivity to cardiac dyssynchrony compared to longitudinal strain?
Circumferential deformation may offer a more sensitive noninvasive measure of cardiac dyssynchrony compared to longitudinal strain.
Dyssynchrony assessed by longitudinal motion is less sensitive to dyssynchrony, follows different time courses than those from circumferential motion, and may manifest CRT benefit during specific cardiac phases depending on pacing mode. These results highlight potential limitations to epsilonll-based analyses and support further efforts to develop noninvasive synchrony measures based on circumferential deformation.
Helm et al. (2005) studied this question.