February 1, 2017Diabetes Metabolic Syndrome and Obesity187 citationsOpen Access

Association between obesity and heart rate variability indices: an intuition toward cardiac autonomic alteration a risk of CVD

RYRam Lochan YadavThe University of Melbourne PYPrakash Kumar YadavHospital and Rehabilitation for Disabled Children LYLaxmi YadavIndian Institute of Management Lucknow

Structured PICO

Is increased WHR associated with altered heart rate variability indices in obese individuals?

Population

Obese individuals defined by BMI

Intervention

Increased Waist-to-Hip Ratio (WHR)

Outcome

Heart rate variability (HRV) indices (cardiac parasympathetic and sympathetic activity)surrogate

Increased WHR is a stronger indicator of adverse cardiac autonomic alterations than BMI in obese individuals, suggesting a higher risk of cardiovascular morbidity.

Abstract

Increased WHR, by far an indicator of visceral adiposity, was strongly associated with reduced cardiac parasympathetic and increased sympathetic activity in obese individuals defined by BMI. However, BMI itself has a weak relationship with HRV cardiac autonomic markers. Thus, even with a slight increase in WHR in an individual, there could be a greater risk of cardiovascular morbidity and mortality brought about by cardiac autonomic alterations.

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