March 18, 2010Open Access

VEGF-A165b Is Cytoprotective and Antiangiogenic in the Retina

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Abstract

The survival effects of VEGF-A(165)b signaling can protect the retina from ischemic damage. These results suggest that VEGF-A(165)b may be a useful therapeutic agent in ischemia-induced angiogenesis and a cytoprotective agent for retinal pigment epithelial cells.

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Magnussen et al. (Thu,) studied this question.

synapsesocial.com/papers/69d9263ff20ef2633068442d https://doi.org/https://doi.org/10.1167/iovs.09-4296

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5Autocrine effects of IGF-I-induced VEGF and IGFBP-3 secretion in retinal pigment epithelial cell line ARPE-192004 · 75 citations

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