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August 25, 2009British Journal of CancerOpen Access

VEGF121b, a new member of the VEGFxxxb family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo

E S Rennel Alexander H. R. Varey A. J. Churchill E R Wheatley LaMonica V. Stewart S. J. Mather David O. Bates SJ Harper

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Abstract

Here we identify a second member of the family, VEGF(121)b, with similar properties to those of VEGF(165)b, and underline the importance of the six amino acids of exon 8b in the anti-angiogenic activity of the VEGF(xxx)b isoforms.

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Rennel et al. (2009) studied this question.

synapsesocial.com/papers/69d9263ff20ef26330684430 https://doi.org/10.1038/sj.bjc.6605249

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