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A new tandem route leading to imidazo[1,2‐ a ]pyridines has been explored through the direct amination of aryl propargylic alcohols with 2‐aminopyridines and their subsequent intramolecular cycloisomerization. A ZnCl 2 /CuCl system has been developed to promote this transformation, which resulted in various imidazo[1,2‐ a ]pyridines in moderate to good yields.
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Liu et al. (2011) studied this question.
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