Malignant pericardial effusions are frequently caused by solid tumors like lung adenocarcinoma, often present with cardiac tamponade, and carry a high mortality rate with limited treatment options.
This study presents the largest systematic review on malignancy-induced pericardial Effs to date. Notably, solid tumours, and specifically lung adenocarcinomas, are common culprits. Malignant pericardial Effs are often severe, with a majority of patients presenting with cardiac tamponade. Overall, treatment options are limited, and the associated mortality rate is high.
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Mudra et al. (2024) studied this question.
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