Is there an association between heart rate variability and inflammatory markers in first-episode depressed patients with different sleep quality?
The relationship between systemic inflammation and autonomic dysfunction in depression is modulated by the severity of sleep disturbances.
The interaction between systemic inflammation and autonomic dysfunction appears to vary with sleep disturbance severity in depression. These findings highlight the importance of considering sleep disturbance stratification when evaluating physiological alterations in depressive disorders. Further studies are needed to clarify the underlying mechanisms and potential clinical implications of these associations.
Alimu et al. (Thu,) studied this question.