Why the study?
Does Lipoprotein Lipase bound to Apolipoprotein B lipoproteins accelerate clearance of postprandial lipoproteins in humans?
Does Lipoprotein Lipase bound to Apolipoprotein B lipoproteins accelerate clearance of postprandial lipoproteins in humans?
Plasma LpL bound to apoB lipoproteins may play a mechanistic role in accelerating the clearance of postprandial intestinal lipoproteins in humans.
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Hypothesis-generating for LpL in postprandial apoB clearance; leaves open effects on CV risk or therapy.
Plasma LpL may act like an apolipoprotein to enhance the clearance of apoB lipoproteins in humans, a mechanism particularly important for intestinal lipoproteins in the postprandial state.
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Zheng et al. (2006) studied this question.
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