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Bioinformatics report reveals an expanded framework for mutational pattern analysis in cancer genomics, highlighting its role in understanding mutation accumulation and aiding diagnostics.
This novel version of MutationalPatterns allows for more comprehensive analyses and visualization of mutational patterns in order to study the underlying processes. Ultimately, in-depth mutational analyses may contribute to improved biological insights in mechanisms of mutation accumulation as well as aid cancer diagnostics. MutationalPatterns is freely available at http://bioconductor.org/packages/MutationalPatterns .
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Manders et al. (2022) studied this question.
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