Why the study?
Are baseline and longitudinal increases in diastolic blood pressure associated with greater white matter hyperintensity volume?
Are baseline and longitudinal increases in diastolic blood pressure associated with greater white matter hyperintensity volume?
Elevated and increasing diastolic blood pressure is linked to increased white matter hyperintensity volume, especially in black individuals.
DBP monitoring may help stratify WMH risk especially in blacks; leaves open causal effects and intervention benefits.
Baseline DBP and longitudinal increases in DBP were independently associated with a greater WMHV, and the association between DBP and WMHV was greatest among blacks.
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Marcus et al. (2011) studied this question.
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