Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
February 23, 2018Nature CommunicationsOpen Access

Genetic study links components of the autonomous nervous system to heart-rate profile during exercise

View Full Paper
Ask AI
Bookmark
Share

Population

58,818 UK Biobank individuals

Design

Cohort

Authors

NVNiek VerweijYVYordi J. van de VegtePHPim van der Harst

Discussion

Loading...

Member takes

Overview

Loci linked to exercise HR dynamics extend autonomic genetic insights; leaves open causal effects on mortality or clinical utility.

Structured PICO

P
Population
58,818 UK Biobank individuals
O
Outcome
Heart rate (HR) increase and HR recovery during and after exercisesurrogate

A large-scale genome-wide analysis identified 25 independent SNPs associated with heart rate increase and recovery during exercise, highlighting the genetic role of the autonomic nervous system in heart rate response.

Cite This Study

Verweij et al. (2018) studied this question.

synapsesocial.com/papers/69d962505e5bcb4e3b835f57https://doi.org/10.1038/s41467-018-03395-6
View Full Paper
Ask AI
Bookmark
Share