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Clinical report demonstrates hypercapnia-induced cerebral hyperperfusion in hospitalized patients, indicating an underrecognized cause of unexplained neuropsychiatric symptoms.
With the inception of ASL as a routine perfusion imaging technique, hypercapnic-associated cerebral hyperperfusion will be recognized more frequently and may provide an alternative cause of unexplained neuropsychiatric symptoms in hospitalized patients. In a similar fashion, hypocapnia may account for a subset of patients with normal MR imaging examinations with poor ASL perfusion signal.
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Pollock et al. (2008) studied this question.
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