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Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate | Synapse

October 15, 2004

Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate

Key Points

Key points are not available for this paper at this time.

Abstract

By decreasing drug loading per antibody, the therapeutic index was increased demonstrating that drug loading is a key design parameter for antibody-drug conjugates.

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Cite This Study

Hamblett et al. (Fri,) studied this question.

synapsesocial.com/papers/69d964848988aeabbe685211 https://doi.org/https://doi.org/10.1158/1078-0432.ccr-04-0789

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