Why the study?
Does intramuscular alipogene tiparvovec improve postprandial chylomicron metabolism in LPLD patients?
Does intramuscular alipogene tiparvovec improve postprandial chylomicron metabolism in LPLD patients?
Alipogene tiparvovec significantly improves postprandial chylomicron metabolism in patients with lipoprotein lipase deficiency.
Intramuscular administration of alipogene tiparvovec resulted in a significant improvement of postprandial chylomicron metabolism in LPLD patients, without inducing large postprandial NEFA spillover.
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Carpentier et al. (2012) studied this question.
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