Significant metabolic changes can occur within the first eight weeks of treatment with risperidone or olanzapine, highlighting the need for early monitoring.
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Early metabolic monitoring is warranted with risperidone or olanzapine; extends RCT evidence for rapid bidirectional changes.
The fact that significant metabolic changes occurred (both positive and negative) in eight weeks is important to clinical care. Monitoring for metabolic changes may be important within the first eight weeks of treatment, as changes can be determined very early in antipsychotic treatment.
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Kelly et al. (2008) studied this question.
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