Why the study?
Torque teno virus was recently identified as a potential biomarker for immunosuppression and predictor of rejection and infection, prompting evaluation of its kinetics and clinical associations in kidney transplant patients.
Does TTV viral load kinetics predict infection and de novo donor-specific antibodies in kidney transplant patients?
Population
81 kidney transplant patients
Comparison
TTV viral load monitoring across clinical event groups
Design
Single-center prospective observational cohort study
Follow-up
12 months
Authors
Loading...
TTV load kinetics may flag early infection risk after kidney transplant; hypothesis-generating and requires prospective validation before any clinical adoption.
Does TTV viral load kinetics predict infection and de novo donor-specific antibodies in kidney transplant patients?
Early increases in TTV viral load strongly predict infectious events in the first year after kidney transplantation.
Querido et al. (2023) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: