Four low molecular weight gels (LMWGs) with different moduli were fabricated as scaffolds to investigate the differentiation of mesenchymal stem cells (MSCs). The MSCs differentiated to osteoblasts in rigid LMWGs and to chondrocytes in soft LMWGs. The critical modulus to induce the different differentiations was between 10 and 20 kPa.
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Hu et al. (2016) studied this question.
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