Macrophage Infiltration into OmentalVersusSubcutaneous Fat across Different Populations: Effect of Regional Adiposity and the Comorbidities of Obesity
Structured PICO
P
Population
Populations with varying regional adiposity and comorbidities of obesity
C
Comparator
Subcutaneous fat
O
Outcome
Macrophage infiltration into omental fatsurrogate
Macrophage infiltration into omental fat is exaggerated by central obesity, providing a potential pathophysiological link to increased risk of diabetes and coronary heart disease.
Authors
Discussion
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Implication
May mediate obesity-related cardiometabolic risk via omental inflammation; hypothesis-generating and leaves causal role open.
Cite This Study
Harman‐Boehm et al. (2007) studied this question.