Non-surgical periodontal treatment resulted in a significant decrease of acetic acid, propionic acid, butyric acid levels and increase of formic acid level in gingival crevicular fluids in patients with G-AgP, accompanied by improvement in clinical parameters. A marked lower level of formic acid, as well as higher levels of acetic acid, propionic acid and butyric acid in gingival crevicular fluid of patients with G-AgP was consistent with periodontal pathogen infection.
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Lu et al. (2013) studied this question.
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