Experimental animal study demonstrates prolonged survival and reduced glomerulonephritis in lupus-prone mice, suggesting a protective therapeutic role for anti-DFS70 autoantibodies.
anti-DFS70 attenuated the progression of glomerulonephritis and prolonged the survival time. Circulating anti-DFS70-autoantibodies may confer a protective role against renal injury in murine-lupus-nephritis. Our data may propose a novel therapy approach for lupus patients.
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Aljadeff et al. (2020) studied this question.
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