What question did this study set out to answer?

To examine the association between prenatal exposure to selective serotonin reuptake inhibitors and the risk of autism spectrum disorder or developmental delay in offspring.

April 15, 2014PEDIATRICSOpen Access

Prenatal SSRI Use and Offspring With Autism Spectrum Disorder or Developmental Delay

View Full Paper

Ask AI

Bookmark

Authors

RHRebecca A. HarringtonJohns Hopkins University LLLi-Ching LeeUniversity of North Carolina at Chapel Hill RCRosa M. CrumManitoba Health

Discussion

Member takes

Implication

Observational study reports increased susceptibility to autism spectrum disorder and developmental delay in male offspring, highlighting the balance between SSRI benefits and risks.

Key Points

To examine the association between prenatal exposure to selective serotonin reuptake inhibitors and the risk of autism spectrum disorder or developmental delay in offspring.
Evaluated neurodevelopmental outcomes in offspring following maternal prenatal exposure to selective serotonin reuptake inhibitors (SSRIs).
Assessed risks of autism spectrum disorder (ASD) and developmental delay (DD), evaluating sex-specific susceptibility alongside potential recall bias and confounding by indication.
Prenatal exposure to SSRIs was linked to increased susceptibility to ASD or DD among male offspring.
Evidence across published literature remains inconsistent, with residual confounding by indication and recall bias posing ongoing methodological limitations.
Confirmation of developmental delay associations warrants validation in larger sample sizes.

Cite This Study

Harrington et al. (2014) studied this question.

synapsesocial.com/papers/69d9aa22387cf70698685075 https://doi.org/10.1542/peds.2013-3406

View Full Paper

Ask AI

Bookmark

Implication

Observational study reports increased susceptibility to autism spectrum disorder and developmental delay in male offspring, highlighting the balance between SSRI benefits and risks.

Prenatal SSRI Use and Offspring With Autism Spectrum Disorder or Developmental Delay

Discussion

Member takes

Implication

Key Points

Cite This Study

Prenatal SSRI Use and Offspring With Autism Spectrum Disorder or Developmental Delay

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider