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The addition of rituximab to the CHOP regimen increases the complete-response rate and prolongs event-free and overall survival in elderly patients with diffuse large-B-cell lymphoma, without a clinically significant increase in toxicity.
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Coiffier et al. (Thu,) studied this question.
synapsesocial.com/papers/69d9af2b387cf7069868519e — DOI: https://doi.org/10.1056/nejmoa011795
Bertrand Coiffier
Université Claude Bernard Lyon 1
Éric Lepage
Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean
Josette Brière
Délégation Paris 7
New England Journal of Medicine
Assistance Publique – Hôpitaux de Paris
Université Claude Bernard Lyon 1
Hôpital Saint-Louis
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