Is depression associated with mortality over long periods of time?
Depression is persistently associated with mortality over long periods, with an emerging association among women in recent decades despite improvements in treatment.
The association between depression and mortality persists over long periods of time and has emerged among women in recent decades, despite contemporaneous improvements in the treatment of depression and reduction of stigma associated with depression. Further research is needed to better understand the mechanisms involved.
Gilman et al. (2017) studied this question.